Following the launch of the first low-concentration atropine (0.01% atropine sulfate eye drops) in China—dubbed the "myopia miracle drug"—Renshu Ophthalmology & ENT swiftly listed it, receiving an influx of parental feedback. Queries range from doubts about efficacy and safety to urgent hopes for results. Below are key insights to clarify misconceptions.
Q1: How effective is low-concentration atropine?
To date, atropine eye drops remain the only evidence-based medication proven to delay myopia progression. Studies show that using 0.01% atropine for two years reduces myopia progression by ~60%. For example, if a child’s myopia worsens by 100 degrees annually without treatment, atropine can typically limit progression to ~40 degrees/year—a significant slowdown.
Q2: Is low-concentration atropine safe?
Like all medications, side effects may occur. A small subset of children may experience photophobia or blurred near vision. However, compared to high-concentration formulations, low-concentration atropine causes minimal systemic reactions (e.g., facial flushing, dry mouth) and milder, less frequent ocular side effects. Rebound effects post-discontinuation are rare.
For photophobia or blurred near vision:
· Use sunglasses or wide-brimmed hats.
· Improve accommodative function via training if needed.
Q3: Is low-concentration atropine suitable for all children?
No. It is primarily recommended for:
· Ages 4–16 years with true myopia ≥50 degrees.
· Annual myopia progression ≥75 degrees.
Exclusions apply for contraindications (e.g., atropine allergy, glaucoma, elevated intraocular pressure, history of eye trauma, or poor accommodative function). Use only after comprehensive evaluation by an eye care professional—never self-administer!
Q4: How to use low-concentration atropine properly?
· Administer 1 drop in each eye before bedtime.
· Close eyes tightly post-application; press the inner corner gently with fingers for 1–2 minutes to minimize systemic absorption.
· Follow up with an eye specialist 1–2 weeks later to monitor safety and efficacy.
· Continuous use for ≥2 years is advised, with gradual tapering to avoid rebound axial elongation. Sudden discontinuation may accelerate myopia progression.
Q5: Does low-concentration atropine eliminate myopia concerns?
No. Atropine is one tool among many. Pair it with:
· Daily 2-hour outdoor activities.
· 20-20-20 rule: After 20 minutes of near work, look at something 20 feet away for ≥20 seconds.
· Proper reading posture.
Combining atropine with optical interventions (e.g., glasses, OK lenses) yields synergistic effects. Atropine slows progression, while optics reduce fatigue. However, uncorrected refractive errors (e.g., failing to prescribe glasses when needed) undermines atropine’s efficacy.
Final Note:
Low-concentration atropine is a valuable aid but not a cure. Rational use—under medical guidance and combined with healthy habits—is key to safeguarding children’s vision.
